Thursday, November 28, 2019

Gods Touch free essay sample

When I was six, I was a bundle of energy and couldnt sort out the many thoughts that loomed in my head. After many evaluations I was labeled with Attention Deficit Disorder (ADD). This got me assigned to special education classes, but the school made no attempt to discover the cause. Confusion and lack of concentration made sitting in a classroom almost impossible. My classmates would antagonize me, knowing I had so much suppressed enrgy causing me to react to the least distraction. Eventually I was placed in special education, located in another elementary school, where I could have special help with my hyperactivity. About this time my parents discovered that my allergies were from chemicals, preservatives and food colorings. Later it was discovered that my first grade math teacher (who also suffered from allergies) had her room cleaned with strong chemicals every night. It was this pungent smell that triggered many reactions in my body. We will write a custom essay sample on Gods Touch or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page But I was teased and ridiculed by other kids, called stupid because I was sitting in special classes, which continued for the several years. School officials put a lot of pressure on my parents to put me on the Ritalin, a drug for hyperactivity. My parents reluctantly did, even though my behavior at home was very different from at school. That same year my family joined First Baptist Church of Hartford. This divine influence on Sunday afternoons began to change me. The people at the church were nice to me, which was different. I was used to kids picking on me. At First Baptist, where we were the only white family, I found agape/love, which was missing in my life. I met many invaluable friends and learned what it is like to be the minority. One day I was in the basement of the church where I saw a frail black woman stumbling as she walked. She must have been eighty. She was excited and I wondered why. Soon after, a spry lady returned. I understood. The young woman who was filled with the Spirit of God was laying her hands on the sick and crippled people of the congregation. They were being healed. I walked to the pulpit and asked her to heal my hyperactivity and my allergies. She touched my forehead and I fell straight back. Embarrassed, I jumped up with all my might, but when she touched me again and I was out cold. I woke up ten minutes later with a blanket over me. My friends said I had been slain in the Spirit. Since then my life has changed. I immediately stopped taking Ritalin. I was moved out of Special Education classes and placed in the regular classes where it was discovered that I was well ahead of most of the other students. My social worker, who knew nothing of my healing experience, called my transition into the regular classroom a miracle. Miracle? Faith? The loving persistence of my parents? You can decide. I only know that all our journeys in life have a purpose and become our driving force to improve life for ourselves and for others.

Monday, November 25, 2019

How to Become a Meteorologist at Any Age

How to Become a Meteorologist at Any Age If you or someone you know watches the Weather Channel for hours at a time, gets excited when weather watches and warnings are issued, or always knows what this and next weeks weather will be, it may be a sign that a meteorologist in-the-making is in your midst. Heres my advice (from a meteorologist herself) on how to become a meteorologist- regardless of your education level. Elementary, Middle, and High Schoolers   Find Ways to Focus on Weather in the ClassroomMeteorology isnt a part of a core curriculum, however, most science classes do include lesson plans on weather and the atmosphere. Although there may not be many chances to include weather in daily learning, one way to express your individual interest is to make use of any choose your own show-and-tell, science project, or research assignments by focusing on a weather-related topic. Be Math-MindedBecause meteorology is whats called a physical science, a solid understanding of mathematics and physics is important in order for you to grasp the advanced concepts youll learn later in your weather studies. Be sure to take courses like Calculus in high school- youll thank yourself later! (Dont be discouraged if these subjects arent your favorites...not all meteorologists were members of the math club.) Undergraduate Students   A Bachelors degree (B.S.) is typically the minimum requirement needed to obtain an entry-level meteorologist position. Unsure if youll need more training? One simple way to find out is to search the job boards of companies youd like to work for or do a Google search for job openings for a position you think youd like to do, then tailor your skills to those listed in the position description. Choosing a universityLess than 50 years ago, the number of North American schools offering degree programs in meteorology was under 50. Today, that number has nearly tripled. Those accepted as top schools for meteorology include: Pennsylvania State University (University Park, PA),Florida State University (Tallahassee, FL),and the University of Oklahoma (Norman, OK). Are Internships a Must Do? In a word, yes. Internships and co-op opportunities provide hands-on experience, give entry-level resumes a boost, and allow you to explore different disciplines within meteorology which will ultimately aid you in discovering which area (broadcasting, forecasting, climatology, government, private industry, etc.) best suits your personality and interests. By connecting you with a professional organization, a diversity of scientists, and perhaps even a mentor, an internship also helps build your professional network and network of references. Whats more, if you do a stellar job as an intern youll likely increase your chances of getting employed at that company after graduation. Keep in mind that you wont be eligible for most internships until your Junior year. Even so, dont make the mistake of waiting until the summer of your Senior year to get involved- the number of programs accepting recent graduates is far and few between. What sorts of opportunities should you, an underclassman, consider in the meantime? Possibly a summer job. Most weather internships are unpaid, so working in the summers prior can help ease that financial burden. Graduate-Level Students   If your heart is set on a career in atmospheric research (including storm chasing), teaching in a university setting, or consulting work, you should be prepared to continue your education at the masters (M.S.) and/or doctorate (Ph.D.) levels. Choosing a graduate degree programWhile returning to your alma mater is one option, youll also want to shop around for schools whose facilities and faculty support research that matches your interests. Professionals   The above advice is helpful to individuals planning their academic career, but what options exist for individuals already in the workforce? Certificate programsCertificates of Meteorology are a great way to gain training in weather without the full commitment of entering into a degree program. Not to mention these are earned by completing a fraction of the coursework required for degree programs (10-20 semester hours vs. 120 or more). Some classes can even be completed online in a distance learning manner. Well-known certificate programs offered in the U.S. include Penn States Undergraduate Certificate in Weather Forecasting  and the Broadcast and Operational Meteorology certificate programs offered by Mississippi State.  Ã‚   Leisurely Meteorologists Not interested in going back to school or participating in a certificate program, but still want to feed your inner weather geek? You could always become a citizen scientist. Whatever your age, its never too early or too late to grow your love and knowledge of weather!

Thursday, November 21, 2019

IT'S AN AD,AD,AD,AD WORLD Essay Example | Topics and Well Written Essays - 750 words

IT'S AN AD,AD,AD,AD WORLD - Essay Example One would ask 'why people switch to buying online rather than visiting stores and feeling the actual experience. Online Shopping is shopping you do online. There are sites that let you buy directly from manufacturers, online versions of regular retail stores, auctions, specialty sites, comparison sites, group buying sites and so on. With companies like e-bay and Amazon, life has become easier for the firms as these sites contain not just only catalogs but also information about the related products which the previous buyers had viewed or tagged before buying the particular product. This adds to the ease of making decision for the customer. Further such sites also allow giving technical support to both the firm and the customer. For example e-bay provides seller tools to help run a business more efficiently, such as 'Turbo Lister' and 'Selling Manager'. The world is changing rapidly and therefore it is an agile competition overall. Each organization requires a perfect strategic edge in order to maintain or improve its clientele. The Web is regarded as the database of databases and in current perspective it has eased the search criteria for every individual involved in buying or selling online. But the point raised is of quality, as so far, the quality sources are difficult to find unless you have the right to enter into the virtual libraries of this world. Since it is more feasible to buy online so one may wonder how easy it gets to buy online, you simply have to type in a word or a phrase which best describes what you are looking for. You can use the product name, manufacturer or type. After you enter your search words, you'll get a list of items matching your description. Here you can witness the resource description as it contains almost all information required for buying purposes. These catalogs allow you to have a feel of the actual equipment and also provide information about the complements (add-ons) you can apply to your product. Simply click on any link for get more specifics. Many businesses have online catalogs. First you need to log on to any desirable site and the next thing you would do is, simply search for the product and make a decision. Firms have been using different strategies in order to attain a higher market share. They, not only advertise using the mainstream Web applications but also acquire information of users from different sites that have member areas, however these sites only provide data of those members who are willing to be public. The firms use this data and attract customers by sending them e-mails which carry the producers' taglines and the links to the ordering sites. This is rather a direct marketing tool used by firms and it has great potential in delivering quality ads to the target customers but the problem is of privacy infringement and therefore only a small number of persons contacted respond to these e-mails. The main forms of ads present on the Web are in forums, blogs, main pages, search engines and reference sites. In these ads, only the main content is highlighted that is they become more appealing to everyone. These ads attract about 1 out of the 20 visitors who would go for the product and view its features. Producers expose there products on the global stratum thereby attracting different people form different cultures. These ads

Wednesday, November 20, 2019

The United States has several laws that are intended to further fair, Research Paper

The United States has several laws that are intended to further fair, balanced, and competitive business practices. Do you think that such laws are effective If so, why If not, why not - Research Paper Example Numerous attempts have been made by the United States to make sure that regulatory systems exist to control monopolistic entities and aggressively enterprising organizations. This control is geared towards not only protecting consumers, but also smaller business trying to grow. Numerous laws have been enacted over the years, for example, the Clayton Act to work towards preventing monopolies. Collectively the laws are referred to as antitrust legislation. This paper investigates the effectiveness of such laws within the United States. The courts have a tendency of being vague when it comes to antitrust regulations. According to the legal systems, thee antitrust laws are intended for the promotion and preservation of competition and enterprise system that is free (Blaisdell, 2008). This vague definition does not do much to enlighten one who wants to know about the laws or is doing business and wants to abide by them. There is no clear layman explanation of these laws and their application. The only way one can have a better understanding of the antitrust laws is by looking at the ruling of cases heard before. The reality of the matter is that interpreting these laws whether in theory or practically can lead to wrong conclusions. The interpretation of the laws by the legal infrastructure make one assumption that the independence of buyers and sellers in the business decision making process encourages completion. The decisions can be made by competitors who will agree on market shares, product restrictions among other things. If these decisions are made independent of the consumer, they might end up suffering as they are not involved in the decision making process. The exclusion of the customer needs within the decisions made by companies may end up limiting choice. The decisions made by the companies may be legally sound but logically, they are hindering the intent of the competition. There is a necessity to set up robust infrastructure to ensure that antitrust

Monday, November 18, 2019

Westfailure System by Susan Strange Essay Example | Topics and Well Written Essays - 2000 words

Westfailure System by Susan Strange - Essay Example On social sphere, strong connection of social suffering with economic inequality causes wide gap between rich and poor classes, which potentially leads to uprisings. Thus, current power balance in terms of state sovereignty cannot manage all the domestic and global challenges the world faces today. On another hand, Mearsheimer’s ‘E.H.Carr vs. Idealism: The Battle Rages On’ (2005) discusses the role of power from both realist and idealist perspectives. Precisely, the author wants to draw the line and find possible compromise in describing state’s nature between its realist willingness to obtain power and proclaimed liberal ideals. Moreover, the author raises deep concern on neglecting of realist thinkers in contemporary academic circles. Even though states during post-Cold War world justify their actions by idealist rhetoric, Mearsheimer by citing Carr blames them to hide the real power interests behind them. Thus, explaining contemporary states and their be havior on international stage in only liberal terms is the wrong way of understanding global reality.2. State and power arguments in the presented articles and commonalities between themSpecifically, both authors construct their arguments by using concepts of state and power in different environments. In this section, there is a detailed description of the arguments presented in both researches with summarizing commonalities between them.As for Strange, she sees state in the broader context than only through appearance as political entity.

Friday, November 15, 2019

Selective Toxicity Of Anti Cancer Agents Biology Essay

Selective Toxicity Of Anti Cancer Agents Biology Essay Cancer is known to be caused by a large group of various diseases, all involved in cellular malfunction. It dates back to about 1600 BC when it was first found in an Egyptian papyrus (Wu et al, 2006) and thought to be incurable till surgery and radiation became the means of treatment in the mid-1900s. After many years it was realised that using either or combination of treatment, metastatic cancer could not be controlled and in order to gain therapeutic effect, the therapy had to reach every organ of the body. Research in drug discovery and development now focuses on using chemotherapy especially those that are selectively toxic e.g. antimetabolites (Thurston, 2007). It is not fully understood why they are selectively toxic but they are more effective on tumour cells because they are able to divide faster that healthy cells. Selective toxicity was defined as materials that are able to damage some types of cells and not the others (Albert, 1951). Even though mortality rate has not imp roved much, characteristics and pathways of cells in different tumours have been identified so as to develop therapies for specific tumour. The therapies developed either target protein that cause or are involved in development of tumour directly or by targeting drugs to the tumour. Examples of new drugs that have resulted from advances in drug discovery are (Narang Desai, 2009) : Imatinib (Gleevec) inhibits binding of protein (BCR-ABL) which is found in CML tumour cells. Gefitinib (Iressa1) inhibits epidermal growth factor receptorà ¢Ãƒ ¢Ã¢â‚¬Å¡Ã‚ ¬Ãƒ ¢Ã¢â‚¬Å¾Ã‚ ¢s. It is used to treat lung cancer. Trastuzumab (Herceptin1) is another monoclonal antibody that binds the cell surface HER2/neu (erbB2) receptor and is used in treating erbB2+ breast cancer. This report will focus on principles and challenges of selective toxicity of chemotherapy, how they work, the limitations of the current chemotherapy and ways to improve drugs. MECHANISM OF ACTION Chemotherapy drugs are able to move throughout the body to get to where they are intended by entering the bloodstream through an injection, a drip which are usually through a vein or as capsules and tablets. For chemotherapy to work it is important to understand cell cycle, this is because chemotherapy drugs work mainly on actively reproducing cells in the body where some drugs attack particular phases of the cell cycle like the S phase. In cancerous cells, the checkpoints are damaged causing the cancer cells to continue to grow out of control. Chemotherapy works by damaging the genes present inside the nucleus of cells. Some drugs work by damaging cells when they are beginning to divide or while copies are being made. Chemotherapy drugs cause the cancerous cells to think that their lifespan has finished which leads to apoptosis. There are different classes of selective toxicity drugs which have different methods for killing cancerous cells, some of which are below(ACS, 2013): Alkylating agents (e.g. busulfan) are selectively toxic to DNA, where they damage DNA so as to prevent cancer cells from reproducing. Active in all the phases of cell cycle and are used to treat a wide variety of cancer like leukaemia Antimetabolites(5-fluorouracil), these agents alter DNA and RNA growth by replacing building blocks normally present in DNA and RNA. They work in the S phase and are used to treat breast cancer. Anti-tumour antibiotics/Anthracyclines (Doxorubicin) are also important as they affect the enzymes that contribute to DNA replication. Other cancer drugs- these are not classified as chemotherapy drugs and they are still new. There are different types, the active and passive where active stimulates the immune system to attack the disease and passive(monoclonal antibody, e.g. Rituximab which binds to particular substances) uses antibodies that were made synthetically. In 2010, the first vaccine for cancer called the Provenge for prostate cancer was approved by the FDA (ACS, 2013). Below Figure 1 shows the new selectively toxic agents that target specific sites and how they influence those sites. Figure : Shows new group of anti-cancer agents designed to target specific protein that contributes to growth of tumour (Wu et al, 2006). PRINCIPLES Chemotherapy drugs that are selectively toxic have been the first choice of treatment for many cancers and there are over 100 drugs in the market today (ACS, 2013) used alone or with other treatments. It is also important to understand how these drugs work so doctors (oncologists) can predict which drugs can be combined with them and how often each drug can be administered to patients. There are three key goals of these chemotherapy treatment (ACS, 2013): The most important goal of chemotherapy is to cure cancer where the cancer/tumour is cleared from the system. There are no guarantees with this treatment as it might even take years for a patient to be cured of cancer. In a situation where cure is not possible it is important to control the disease by shrinking cancer or stopping it from growing or spreading. This is also important as it gives the possibility of a longer life because it is controlled like a disease that is chronic like diabetes. Last is palliation, which is important when cancer is at an advanced stage. Chemotherapy drugs in this case can be used to relieve symptoms or improve the patients quality of life. LIMITATIONS Normal cells that divide rapidly are damaged by these chemotherapeutic agents because they cannot differentiate between cell reproducing normal tissues and cancer cells as they are not highly selective therefore causing the following side effects (Salmon Sartorelli, 1998). Bone marrow suppression because the bone marrow cells normally divide quickly Alopecia because hair follicle cells are able to divide frequently as well GI disturbances (Nausea and Vomiting) due to mucosal cells dividing rapidly Some of these agents cause serious side effects which may lead to permanent damage to a vital organ (liver, lungs) in the body, cause infertility, heart problems or disrupt the central nervous system by causing damage. Another big problem is the development of resistance of chemotherapy drugs to treating different tumours which can occur before treatment with drug or over time after treatment. In some cases continuous/prolonged exposure to one chemotherapy drug can cause resistance to other compounds with similar structures (Akhdar, 2012). Resistance can also develop if the drug concentration in the patient is reduced due to diminished cellular diffusion or increased drug efflux. Chemotherapy treatment is also expensive and might take a couple of years before the disease is eradicated. In some cases the treatment does not work or may not destroy the cancer completely. Lastly, it makes the immune system very weak. Ways to Improve Drug A way of improving drug or avoiding resistance is using a combination of variety of cytotoxic agents as it allows prompt attack of different biological targets therefore increasing the effect of the treatment (Thurston, 2007) or with other agents that act as sensitizers to these cytotoxic agents (Narang Desai, 2009). Another way is developing new formulations that can prevent the severe side effects associated with a particular drug e.g. Doxorubicin caused cardiotoxicity but with new formulations like the liposomal formulation there are decreased side effects that are manageable and due to the selectivity of the new drug it works better than the conventional anthracycline. The use of adjuvants can minimize toxicity of anticancer drugs, therefore reducing the side effects of some of the drugs. A better diet is also advised, especially with avoiding food that cause inactivation of the drugs. Vitamin C found in citrus fruits like oranges have been found to influence anticancer drugs and reduce toxicity to the body (Salmon Sartorelli, 1998). Conclusion It can be concluded that there are three important factors to consider in selective toxicity of a drug, they are the tumour, drug and most especially the host. There have been a lot of improvement with using chemotherapy to manage cancer even though they cause severe side effects and resistance. Other challenges faced are the cost, time involved and the high mortality rate. This has brought about increase in effort of scientists to search for ways for the body to fight cancer tissue and find better cytotoxic agents to fight cancer cells.

Wednesday, November 13, 2019

Exile And Pain In Three Elegiac Poems Essay -- essays research papers

There is a great similarity between the three elegiac poems, The Wanderer, The Wife of Lament, and The Seafarer. This similarity is the theme of exile. Exile means separation, or banishment from ones native country, region, or home. During the Anglo Saxon period, exile caused a great amount of pain and grief. The theme is shown to have put great sadness into literature of this time period. The majority of the world's literature from the past contains the theme of exile. The Wife of Lament is another perfect example of literature with exile, and was written by an unknown author. The most striking example of exile in this poem can be seen in the passage when she says, "A song I sing of sorrow unceasing, the tale of my trouble, the weight of my woe, woe of the present, and woe of the past, woe never-ending of exile, and grief, but never since girlhood greater then now." The woman's husband left her in a life of exile, after he left. She is constantly looking for him, and finds a life that is quite similar to being locked away in prison. She is locked up in a cave under a tree. Her joy comes from thinking that her husband is as miserable as her. In the first passage from the poem, The Wanderer, it speaks of exile by saying, "To the wanderer, weary of exile cometh Gods pity, compassionate love, though woefully toiling on wintry seas with churning oar in the icy wave, homeless and helpless he fled from fate." It can be easily seen...